Performance of poly ether sulphone membranes in wearable artificial kidney: study on using additives
Paper ID : 1134-MST2015-FULL
Roshheh Eshraghi *1, Ghassem Amoabediny2, Azadeh Ghaee3, Mohammad Hadi Foroughi Moghaddam4
1unit10-No.18- 9th east- Shahin villa street- Karaj- Alborz
2Department of chemical engineering, Faculty of engineering, University of Tehran, Tehran, Iran
3Division of biomedical engineering, Faculty of New Sciences and Technologies, University of Tehran
4Research center for new technologies in life science engineering, University of Tehran, Tehran, Iran
It is vitally important to recycle dialysate in new wearable artificial kidney systems. This could be possible using porous membranes technology, where the uremic toxins of dialysate pass through the membrane and solve into dialysis solution at the other side of membrane. The recycled dialysate is reused in order to remove uremic toxins. The purpose of this paper is fabrication of membranes with suitable separation ability and biocompatibility, which are used in wearable artificial kidney based on peritoneal dialysis. Thus, flat poly ether sulfone (PES) membranes without and with poly ethylene glycol (PEG 1500 Da) in 4.5% and 9% (wt/wt) and poly vinyl pyrrolidone (PVP) in 2.5% and 5% (wt/wt) additives are fabricated. The membranes were characterized in pure water flux (PWF), mechanical resistance and scanning electron microscope (SEM) (cross section and surface of membranes). The optimized membrane performances in order to remove urea and creatinine are assessed, and the effect of temperature parameter on membranes performance is investigated. The results of mechanical resistance and PWF tests confirmed the suitability for using 2.5% wt PVP and 4.5% wt PEG in comparison to 5% wt PVP and 9% wt PEG membranes. The membrane performance in urea and creatinine separation were investigated in term of concentration driving force and the results showed that 2.5% wt PVP membrane had better performance than 4.5% wt PEG membrane. These were also confirmed with considering the membranes morphology which were illustrated in SEM images.
Wearable artificial kidney based on peritoneal dialysis - flat membrane poly ether sulfone - characterization and performance of membrane - urea and creatinine removal
Status : Paper Accepted (Oral Presentation)